Marfan syndrome life expectancy

When we talk about Marfan syndrome should really talk about Marfan syndrome life expectancy because it is a disease that undiagnosed, timely can lead to the death of the patients.
Marfan syndrome is a genetic disorder (autosomal dominant) characterized by connective tissue damage. This syndrome includes multiple malformations of organs (bones, eyes, skin, intestines, heart and lungs).

Marfan syndrome symptoms

Most of the visible signs or symptoms occur in the skeletal system. The patients  suffering from Marfan syndrome are taller than patients without the disease and arachnodactyly ( very thin and long fingers). Another anomaly in the skeletal system is pectus excavatus (deformity of the anterior wall of the chest which penetrates inside sternum) and scoliosis (abnormality of the spine that consists of spine deformity in the form of the letter S). Other signs include abnormal joint flexibility and sometimes pain in joint.
The most important signs and symptoms  associated with Marfan syndrome are the cardiovascular symptoms. This are mitral or aortic valve prolapse (the most common heart valve abnormality) and aneurysm of the aorta.  Many patients with Marfan syndrom have some type of vision problems of which the most important are myopia (a visual anomaly in which distant objects appear blurred), glaucoma and cataracts. This can severely influence Marfan syndrome life expectancy.

Marfan syndrome life expectancy

Marfan syndrome life expectancy may be different from patient to patient. There is no treatment for the Marfan syndrome, but life expectancy may be influenced by monitoring and treatment of complications that can occur. Marfan syndrome life expectancy increased lately because of the advancement in medical techniques and appearance of new treatments.
Best way to expend Marfan syndrome life expectancy is tracking the aneurysm of the aorta and mitral valve prolapse. This is done by a cardiologist annual control for monitoring the health of the heart valves and the aorta. This is done by performing an ECG or another radiological method for the visualization of the anomaly (such as CT or MRI image). The goal of treatment in Marfan syndrome is to slow the progression of the aortic dilatation and to prevent the dissection of the aorta. Another goal of the treatment is to eliminate arrythmias and diminuate the heart rate.
The skeletal manifestations of this syndrome are also important for Marfan syndrome life expectancy. They can be serious and can affect patients life. To solve these problems are used different kinds of pain medication or muscle relaxants.
Because some of the Marfan symptoms of the spine may be asymptomatic, but serious if are not treated, they can be solved by surgery and thus increase the Marfan syndrome life expectancy.
Lung damage involves spontaneous pneumothorax and Marfan syndrome life expectancy depends on the volume of air in the pleural space.  It may resolve by itself or can be made by chest drainage.
Conclusion

Today patients with this syndrome needs to know is not the end of life and Marfan syndrome life expectancy can be good if patients are addressed in time to the doctor.

Leaking heart valve

Mortality and morbidity thought leaking heart valve are  an important part of cardiovascular pathology.  The main changes in  the study of leaking heart valve involves an evaluation of their function and etiology.
So, rheumatic etiology is declining, while the degenerative and ischemic etiology is growing.
Clinical evaluation methods have the same value (family history, physical examination), but some paraclinical methods ( cardiac ultrasound and Doppler) have an important role.

Types of leaking heart valve

Leaking heart valve may occur at the four heart valve: mitral valve, aortic valve, pulmonary valve and tricuspid valve.
The most common type of leaking heart valve is mitral regurgitation. It is characterized by regurgitation of blood in systole ( contraction of heart) from the left ventricle into the left atrium. There are two causes of mitral regurgitation: acute and chronic. The etiology of mitral regurgitation can be inflammatory, but also degenerative and structural. Chronic mitral regurgitation lead to expansion of left atrium.   Echocardiography provides important information in mitral regurgitation.
Another type of leaking heart valve is aortic regurgitation. It is incomplete closure of aortic valve in diastole (relaxation of heart). Aortic valves are affected primary by acute articular rheumatism, infectious endocarditis and degeneration and it can be acute or chronic.
Two other leaking heart valve are tricuspid regurgitation and pulmonary regurgitation. Tricuspid regurgitation is characterized by regurgitation of blood in systole from the right ventricle into the right atrium because of the incomplete closure of the tricuspid orifice.

Leaking heart valve symptoms

Symptoms of patients with   leaking heart valve depends on regurgitation grade and how to install (suddenly or gradually). Patients with small regurgitation can be asymptomatic. There are some  common  symptoms to the patients with leaking heart valve:
-          dyspnea on effort (shortness of breath or air hunger);
-          cough;
-          angina pectoris on effort (chest pain on effort) or at rest;
-          heart murmur;
-          heart palpitations (heart beats more than 90 per minute);
-          asthenia and adinamie;
-          fatigue;
-          rarely may occur syncope;
-          pale skin on  clinical examination.

Leaking heart valve diagnosis

Positive clinical diagnosis is based on present of heart murmur (systolic or diastolic) with different characters. Most used methods for diagnosis leaking heart valve are echocardiography, chest radiography, electrocardiography and Doppler exam.

Treatment and evolution of patients with leaking heart valve

Treatment of asymptomatic patients with leaking heart valve is not necessary. To the patients with symptoms should avoid exercise and salt. There are also treatments with drugs and surgery for leaking heart valve.
Evolution and prognosis of leaking heart valve depend on the importance blood reflux, of how to install (acute or chronic) and of the etiology. Patients with small or average regurgitation may remain asymptomatic a long time, but patients with complications (infectious endocarditis, atrial fibrillation) have obvious symptoms. Patients with acute leaking heart valve have serious prognosis.