Myocarditis

Myocarditis is a type of heart disease that is the inflammation of myocardium. Myocardium is the part of the heart that has more muscles compared to other parts. Myocarditis is caused by infections that can be viral or bacterial. The usual signs of myocarditis are heart failure quickly, chest pain and sudden death. There are various kinds of heart diseases from which people suffer. The neglect and wrong diagnosis of the disease can ave fatal consequences and at times affects the other parts of the body as well. Any kind of symptoms should not be neglected. Expert help should always be taken when there is need. Heart diseases are rampant among those who lead an extremely stressful life that involves physical and mental stress. However there are other causes as well like genetic and congenital defects that cause heart disease. The signs and symptoms showed by individuals having myocarditis are usually varied.

People having myocarditis have signs like stabbing chest pains, palpitations that is caused by arrhythmias, congestive failure of the heart. The congestive heart failure leads to hepatic congestion, edema and a feeling of breathlessness. Myocarditis can also cause fever that is the rheumatic fever and sudden death at times. Myocarditis is most of the times caused by viral infections due to which there are symptoms like diarrhea, pain in the joints and extreme fatigue. Myocarditis is linked with pericarditis often. Many patients show signs and symptoms that points to concurrent myocarditis and pericarditis. There are many factors that leads to the formation of myocarditis in the heart. The factors causing myocarditis have been identified by experts.

Viral infections like the presence of viruses like enterovirus, Coxsackie virus, rubella virus, polio virus, cytomegalovirus, and hepatitis C can cause myocarditis. Bacterias like brucella, corynebacterium diphtheriae, gonococcus, haemophilus influenzae, actinomyces, tropheryma whipplei, and vibrio cholerae are the causes of myocarditis. Spirochetal like borrelia burgdorferi, leptospirosis and protozoal infection like toxoplasma gondii and trypanosoma cruzi are the causes of myocarditis. Parasites like Echinococcus granulosus, visceral larva migrans, Wuchereria bancrofti, schistosoma, Taenia solium and trichinella spiralis. Drugs too are the contributing factors in causing myocrditis. Drugs containing chemotherapy, ethanol, and antipsychotics can cause this heart disease along with toxins and heavy metals. Electric shock, hyperpyrexia, and radiation too causes the disease.

Myocardium can be diagnosed on the results of electrocardiographic results (ECG), elevated CRP and/or ESR and increased IgM (serology). Markers of myocardial damage (troponin or creatine kinase cardiac isoenzymes) are advanced. The ECG show the diffusion of the T wave inversions and the elevations of saddle-shaped ST-segment. These are also found in pericarditis. The best way to detect myocarditis is biopsy of the myocardium that can be done by angiography. The biopsy can be done by the tissue sample of the endocardium and myocardium. A pathologists tests it under light microscopy, immunochemistry and special staining methods. Histopathological features of myocardium are myocardial interstitium accompanied by edema and inflammatory infiltrate, with ample lymphocytes and macrophages. Focal destruction of myocytes are the reasons for failure of myocardial pump.