What is a Heart Attack?

What is a Heart Attack?

Have you ever asked yourself the question what is a heart attack? We all know that it can be deadly and that you need immediate attention if you are having one. However, many people do not know exactly what is going on with the heart during a heart attack. Unfortunately, if more people knew exactly what a heart attack was, as well as the warning signs, then there would not be so many heart attack related deaths.

A heart attack is when the blood flow to part of the heart muscle becomes blocked. When the blood flow becomes blocked it must be restored quickly or the part of the heart that is deprived of blood can die. If you think that you, or someone around you, is having a heart attack then it is important to seek out help immediately. If treatment for a heart attack is started within one hour of when the symptoms start then there is a better chance of the treatment working. Since the heart is the muscle that supplies the rest of your body with oxygen rich blood it is crucial that it is functioning properly. Even a few moments without blood flow to the rest of the body can cause major damage to other organs.

Every year over a million people in the United States have heart attacks. Most of the heart attacks can be attributed to the lifestyle of the person. For instance things such as smoking cigarettes, a lot of stress and a poor diet can contribute to the likelihood that a heart attack will occur. The above mentioned factors can put unnecessary strain on the heart muscle thus causing you to have a heart attack. It is important to call an ambulance if you feel like you are having a heart attack. Since the symptoms can come on suddenly it is best to not wait around before getting help. If you wait too long it may be too late.

Over half of the people who suffer a heart attack die. This is because they did not recognize the warning signs and seek out immediate help. Many people could make a full recover from a heart attack if they would just act a little bit quicker. When the heart is involved it is important to know the details. Being able to answer the question what is a heart attack will ensure that you know what is going on if you begin to feel symptomatic.

Experiencing Heart Symptoms? Read This for Tips

Experiencing Heart Symptoms? Read This for Tips

Heart attack symptoms or also known as a myocardial infarction is the death of heart muscle from the sudden blockage of a coronary artery by a blood clot. Coronary arteries are blood vessels that supply the heart muscle with blood and oxygen. Blockage of a coronary artery deprives the heart muscle of blood and oxygen thus causing injury to the heart muscle.

This injury to the heart muscle causes chest pain and chest pressure sensation and if the blood flow is not restored to the heart muscle within 20 to 40 minutes irreversible death of the heart muscle will begin to occur. Muscle continues to die for six to eight hours at which time the heart attack usually is “complete.” The dead heart muscle is eventually replaced by scar tissue.

Heart Symptoms Causes:

Atherosclerosis is process by which plaques of cholesterol are deposited in the walls of arteries. Cholesterol plaques cause hardening of the arterial walls and narrowing of the inner channel of the artery.

Arteries that are narrowed by atherosclerosis cannot deliver enough blood to maintain normal function of the parts of the body they supply. Atherosclerosis of the arteries that furnish blood to the brain can lead to vascular dementia or stroke.

Atherosclerosis can remain silent in a lot of people for years or decades. It can begin as early as the teenage years but symptoms or health problems usually do not arise until later in adulthood when the arterial narrowing becomes severe.

Smoking cigarettes, high blood pressure, elevated cholesterol, and diabetes mellitus can accelerate atherosclerosis and lead to the earlier onset of symptoms and complications, particularly in those people who have a family history of early atherosclerosis.

Coronary atherosclerosis is the atherosclerosis that causes hardening and narrowing of the coronary arteries. Diseases caused by the reduced blood supply to the heart muscle from coronary atherosclerosis are called coronary heart diseases (CHD).

Coronary heart diseases include heart attacks, sudden unexpected death, chest pain (angina), abnormal heart rhythms, and heart failure due to weakening of the heart muscle.

Conclusion:

At the first sign of heart attack symptoms acting fast can save lives and limit damage to the heart. Treatment is most effective when started within 1 hour of the beginning of symptoms. If you think you or someone may be having a heart attack it is advice to call your emergency numbers within a few minutes or 5 at the most of the start of symptoms.

In case the symptoms stop completely in less than 5 minutes still call your doctor. Take a nitroglycerin pill if your doctor has prescribed this type of medicine.

If you’re looking for a natural solution to prevent heart attack and stroke, the we recommend you to check EDTA Oral Chelation Therapy, which has proven to be very effective in removing arterial plaque that accumulated on your arteries wall.

Ischemic heart disease

Ischemic heart disease

Most of the people in the world suffer from heart disease. In the past couple of decades the number of heart patients have increased tremendously. Th heart is a part of the cardiovascular system and is the most important part of the human body. It is the heart which supply blood to all parts of body cells. The blood pumped by heart carries oxygen which the cells and required. Before knowing about heart disease one must know how people get heart disease. Heart disease is not like a flu or cold which can transfer from one person to another by touching. Many people does not realize that they suffer heart disease unless any major thing happens. Want to know more about heart disease check put the various types of heart disease like Hypertensive heart disease, Cardiovascular disease, Valvular heart disease, Cardiomyopathy, Inflammatory heart disease, Coronary heart disease and Heart failure.

Hypertensive heart disease is a common type of heart disease that most of the people suffer from. This type of heart disease is caused because of high blood pressure. Cardiovascular disease effect the blood vessels and the heart. This heart disease mostly effect arteries and veins. The men who suffers from this type of heart disease their heart muscles are mostly effected but in women it effects the blood vessels. Valvular heart disease as the name suggests is mostly related to the heart valves. This heart disease effect aortic valve stenosis and Mitral Valve prolapse. Cardiomyopathy is also the most common type of heart disease. Cardiomyopathy means heart muscle disease. This heart disease effects the function of myocardium. The people who suffer from this kind of heart disease are at a risk of having sudden cardiac death. Inflammatory heart disease is also very dangerous in which the patient suffer from the inflammation of the heart muscle. Accumulation of atheromatous plaque within the walls of the arteries can cause Coronary heart disease. The heart disease which is caused from any functional cardiac disorder can cause heart failure. From all thee one must have got fair idea about heart disease.

Many people fail to realize they have a heart disease until they face some major problem. The symptoms of heart disease are chest pain, stroke and heart attack. If you find these kind of problems it is suggested to consult the doctor immediately. Get yourself diagnosed properly before opting for any medicine. Some of the common test to be done are If it's not an emergency and a doctor suspects the person could have cardiovascular disease, the doctor can do some tests to find out more about how the heart and blood vessels are working. Some of the tests done for heart disease are Electrocardiogram, Carotid, Echo-cardiogram, Catheterization and Stress test. All these tests are necessary to do if you want to know about the heart disease. Today maximum number of people are getting effected by the heart disease. In order to avoid all complications of heart disease one must also pay attention to their daily diet.

Reperfusion injury

Reperfusion injury has been defined as myocardial tissue blood supply after a period of ischemia. Whether reperfusion merely  accelerates the damage that would have occurred during the initial ischemia  or whether there is a additional injury caused by reperfusion itself is still researched. Although the crucial role of reperfusion injury in revascularization procedures has bees recognized, the etiology and pathogenesis of this phenomenon remain unknown.
Myocardial ischemia accompanied by reperfusion injury followed by complete normalization if it took 5 minutes, by diastolic and systolic dysfunction if ischemia took 15-20 minutes and without return contractile function if ischemia took more than one hour.
The most common cause found in patients who died after reperfusion is hemorrhagic infarction. In myocardial infarction of less than 3 days the cellular response is present throughout the myocardial infarction, in contrast to the distinct zones seen in the non- reperfused myocardial infarctions. Reperfusion itself may produce injury.

The mediators of reperfusion injury

Reperfusion injury

One of the mediators of reperfusion injury is oxygen free radicals. The possible role of reactive oxygen species in reperfusion injury has evolved from our knowledge. They elaborate enzyme systems that rapidly detoxify superoxide and peroxide. The metabolism of reactive oxygen also has damaging effects. The investigators of this event have suspected that even physiological quantities of peroxide may inhibit the aerobic oxidation of pyruvate and thus restrict cellular ATP formation.
Another mediator of reperfusion injury is endothelial dysfunction and microvascular injury. Recent reports indicate that endothelium-dependent relaxation  of coronary microvessels is markedly impaired after ischemia with reperfusion. This microvascular endothelium dysfunction may be caused by blood products or myocardial metabolites that are released during the reperfusion period or by oxygen free radicals.
One of the oldest hypotheses about reperfusion injury involved calcium overload. Other mediators involved in reperfusion injury are altered myocardial metabolism and endogenous protective mechanisms.
There are some cardiovascular risk factors influence reperfusion injury. This are  hypercholesterolemia, very high glucose and hypertension.

Pharmacological methods to attenuate reperfusion injury

There are a number of pharmacological methods for attenuate reperfusion injury. In the treatment of myocardial infarction, restoration of coronary flow as soon as possible is a very important thing to prevent and reduce myocardial necrosis and ischemia. By this treatment ensure a reduction of mortality,  complications and a good prognosis in infarction. Early myocardial reperfusion injury prevent necrosis; in this way systolic and diastolic functions are established and are preventable fatal arrhythmias. In the early hours of  infarction,  reperfusion injury offers the greatest benefits: higher thrombus lysis.
Anti-ischemic therapy and lytic therapy has an important role to reduce myocardial energy demand. There are three revascularizations methods: trombembolitic treatment,  coronary angioplasty and coronary bypass. To thrombolytic treatment add anticoagulant and antithrombotic treatment and GP IIb/IIIa blockers. Thrombolytic agents currently used are streptokinase, tissue plasminogen activator and urokinase.

Conclusion for reperfusion injury

In conclusion the beneficial effect of fast recanalization may be offset by reperfusion injury.